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Article

CYP3A4*1B polymorphism and cancer risk: a HuGE review and meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2013

Zhou Li-Ping, Yao Fan, Luan Hong, Wang Yin-Ling, Dong Xi-Hua, Zhou Wen-Wen, Wang Qi-Hui

Abstract excerpt

CYP450 3A4 (CYP3A4), encoded by the CYP3A4 gene, is a major enzyme catalyzing the metabolism of both endogenous and exogenous agents that may play a role in the etiology of carcinogenesis. Several potentially functional polymorphisms of the CYP3A4 gene have been implicated in cancer risk, but individually published studies have shown inconclusive results. The aim of this Human Genome Epidemiology (HuGE) review...

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PMID: 23179402
DOI: 10.1007/s13277-012-0592-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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