Article
Vitamin D Receptor Polymorphism and Cancer: An Update.
Anticancer research - 1 Aug 2017
Rai Vikrant, Abdo Joe, Agrawal Swati, Agrawal Devendra K
Abstract excerpt
BACKGROUND: Vitamin D mediates its action via vitamin D receptor (VDR) and is involved in a wide variety of biological processes including regulation of cell proliferation and differentiation in normal tissue and apoptosis, and cell adhesion in tumor cells. The study of genetic variations in VDR may elucidate the association of vitamin D levels, its metabolism, and VDR polymorphism with various diseases and...
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