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Article

Gene expression profiles of CYP24A1 and CYP27B1 in malignant and normal breast tissues

6 Dec 2016

Abstract excerpt

Active vitamin D has several antitumor effects, including prodifferentiative, antiproliferative and proapoptotic functions in a number of tissues via its binding to vitamin D receptor. The 24‑hydroxylase (CYP24A1) and 1‑hydroxylase (CYP27B1) enzymes are considered to be pivotal determinants of the local concentration of active vitamin D. The aim of the present study was to investigate the mRNA expression levels...

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PMID: 27922682
DOI: 10.3892/mmr.2016.5992

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