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Article

The associations between CYP24A1 polymorphisms and cancer susceptibility: A meta-analysis and trial sequential analysis.

Pathology, research and practice - 1 Jan 2018

Zhu Man, Qiu Shili, Zhang Xianwei, Wang Yingchao, Souraka Tapara D M, Wen Xue, Liang Chunzi, Tu Jiancheng

Abstract excerpt

PURPOSE: Published data have shown that vitamin D may have a protective effect on cancer development. CYP24A1, the main enzyme responsible for the degradation of active vitamin D, plays an important role in many cancer related cellular processes. Up to now, relationships between CYP24A1 polymorphisms and cancer susceptibility have been widely investigated, whereas the results are inconsistent. The aim of present...

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PMID: 29254801
DOI: 10.1016/j.prp.2017.11.014

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