Article
Genetic Predictors of Circulating 25-Hydroxyvitamin D and Prognosis after Colorectal Cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2020
Neumeyer Sonja, Butterbach Katja, Banbury Barbara L, Berndt Sonja I, Campbell Peter T, Chlebowski Rowan T, Chan Andrew T, Giovannucci Edward L, Joshi Amit D, Ogino Shuji, Song Mingyang, McCullough Marjorie L, Maalmi Haifa, Manson JoAnn E, Sakoda Lori C, Schoen Robert E, Slattery Martha L, White Emily, Win Aung K, Figueiredo Jane C, Hopper John L, Macrae Finlay A, Peters Ulrike, Brenner Hermann, Hoffmeister Michael, Newcomb Polly A, Chang-Claude Jenny
Abstract excerpt
BACKGROUND: Low serum 25-hydroxyvitamin D [25(OH)D] concentrations in patients with colorectal cancer have been consistently associated with higher mortality in observational studies. It is unclear whether low 25(OH)D levels directly influence colorectal cancer mortality. To minimize bias, we use genetic variants associated with vitamin D levels to evaluate the association with overall and colorectal...
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