Article
Mutational profile of endometrial hyperplasia and risk of progression to endometrioid adenocarcinoma.
Cancer - 15 Jun 2020
Russo Mariano, Newell Jordan M, Budurlean Laura, Houser Kenneth R, Sheldon Kathryn, Kesterson Joshua, Phaeton Rebecca, Hossler Carrie, Rosenberg Jennifer, DeGraff David, Shuman Lauren, Broach James R, Warrick Joshua I
Abstract excerpt
BACKGROUND: Endometrial hyperplasia is a precursor to endometrioid adenocarcinoma (EMC), the most common uterine cancer. The likelihood of progression to carcinoma may be evaluated by histologic subclassification of endometrial hyperplasia, although these subclasses are subjective and only modestly reproducible among pathologists. Patient care would be improved by a more objective test to predict the risk of...
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