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Article

Emerging roles of CCM genes during tumorigenesis with potential application as novel biomarkers across major types of cancers

18 Mar 2020

Abstract excerpt

Cerebral cavernous malformations (CCMs) are microvascular anomalies in the brain that result in increased susceptibility to stroke. Three genes have been identified as causes of CCMs: cerebral cavernous malformations 1 [(CCM1) also termed Krev interaction trapped 1 (KRIT1)], cerebral cavernous malformation 2 [(CCM2) also termed MGC4607] and cerebral cavernous malformation 3 [(CCM3) also termed programmed cell...

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PMID: 32186778
DOI: 10.3892/or.2020.7550

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