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Article

The multifaceted PDCD10/CCM3 gene

30 Dec 2020

Abstract excerpt

The programmed cell death 10 (PDCD10) gene was originally identified as an apoptosis-related gene, although it is now usually known as CCM3, as the third causative gene of cerebral cavernous malformation (CCM). CCM is a neurovascular disease that is characterized by vascular malformations and is associated with headaches, seizures, focal neurological deficits, and cerebral hemorrhage. The PDCD10/CCM3 protein has...

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PMID: 34522709
DOI: 10.1016/j.gendis.2020.12.008

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