Article

Comprehensive CCM3 Mutational Analysis in Patients with Syndromic Cerebral Cavernous Malformation

2022-08-26

Abstract excerpt

<title>Abstract</title> <p>Cerebral Cavernous Malformation (CCM) is a vascular disease that affects the central nervous system, which familial form is due to autosomal dominant mutations in the genes <italic>KRIT1/CCM1</italic>, <italic>MGC4607/CCM2</italic> and <italic>PDCD10/CCM3</italic>. Patients affected by the <italic>PDCD10</italic> mutations usually have the onset of symptoms at an early age and a more ag...

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Literature Corpus work: 7c59b73f-bc47-5197-89ab-6bdc7c2ee89e
DOI: 10.21203/rs.3.rs-1991748/v1

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