Article
A Review of Mouse Models of Monogenic Diabetes and ER Stress Signaling.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Salpea Paraskevi, Cosentino Cristina, Igoillo-Esteve Mariana
Abstract excerpt
Diabetes is a major public health problem: it is estimated that 420 million people are affected globally. Monogenic forms of diabetes are less common, but variants in monogenic diabetes genes have been shown to contribute to type 2 diabetes risk. In vitro and in vivo models of monogenic forms of diabetes related to the endoplasmic reticulum (ER) stress response provided compelling evidence on the role of ER...
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