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Article

Evidence for Associations Between Th1/Th17 "Hybrid" Phenotype and Altered Lipometabolism in Very Severe Graves Orbitopathy.

The Journal of clinical endocrinology and metabolism - 1 Jun 2020

Fang Sijie, Zhang Shuo, Huang Yazhuo, Wu Yu, Lu Yi, Zhong Sisi, Liu Xingtong, Wang Yang, Li Yinwei, Sun Jing, Gu Ping, Zhou Huifang, Fan Xianqun

Abstract excerpt

PURPOSE: The purpose of this article is to investigate the characteristics of Th1-cell and Th17-cell lineages for very severe Graves orbitopathy (GO) development. METHODS: Flow cytometry was performed with blood samples from GO and Graves disease (GD) patients and healthy controls, to explore effector T-cell phenotypes. Lipidomics was conducted with serum from very severe GO patients before and after...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32173759
DOI: 10.1210/clinem/dgaa124

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