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M2b macrophage subset decrement as an indicator of cognitive function in Alzheimer's disease

14 Mar 2020

Abstract excerpt

Aim Alzheimer's disease (AD) is a chronic neurodegenerative disease. Various inflammatory processes account for the pathology of AD, and macrophages in particular have a distinct polarization phenotype related to M1/M2 classification. We aimed to investigate macrophage polarization patterns as an indicator of cognitive function in AD. Methods We recruited 54 non‐demented individuals as control and 105 AD patients...

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PMID: 32170772
DOI: 10.1111/pcn.13000

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