Article
Neuroinflammatory phenotypes and their roles in Alzheimer's disease.
Neuro-degenerative diseases - 1 Jan 2014
Wilcock Donna M
Abstract excerpt
BACKGROUND: Alzheimer's disease (AD) is characterized pathologically by the presence of amyloid plaques and neurofibrillary tangles in the brain. While once considered immunologically privileged due to the blood-brain barrier, it is now understood that the glial cells of the brain are capable of complex inflammatory responses. OBJECTIVE: The goal of the study is to assess the neuroinflammatory state of the early...
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