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Article

Immune phenotypes of microglia in human neurodegenerative disease: challenges to detecting microglial polarization in human brains.

Alzheimer's research & therapy - 19 Aug 2015

Walker Douglas G, Lue Lih-Fen

Abstract excerpt

Inflammatory responses in the brain, which can be demonstrated by changes in properties of microglia, the brain-resident macrophages, are a common feature of human neurodegenerative diseases. Different monocyte/macrophage phenotypes have been defined by changes in expression of cytokines, receptors and other markers as a response to different classes of stimuli. Monocytes, macrophages and microglia can have a...

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Identifiers

PMID: 26286145
DOI: 10.1186/s13195-015-0139-9
PMCID: PMC4543480

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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