Article
The interaction of histone modification related H3F3B and NSD2 genes increases the susceptibility to schizophrenia in a Chinese population.
Progress in neuro-psychopharmacology & biological psychiatry - 13 Jul 2020
Liu Wenxin, Fang Yu, Shi Yuan, Cheng Ying, Sun Chuanwen, Cui Donghong
Abstract excerpt
The role of histone modifications in the pathogenesis of schizophrenia has been proposed previously. H3F3B is a member of the histone 3. NSD2 is a histone methyltransferase that mediates dimethylation of Histone 3 lysine 36 (H3K36me2). The aim of the current study was to explore the associations between SNPs within H3F3B gene (rs60700976, rs3214028) and NSD2 gene (rs13148597, rs75820801) and the susceptibility to...
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