Article
Possible association of the semaphorin 3D gene (SEMA3D) with schizophrenia.
Journal of psychiatric research - 1 Jan 2011
Fujii Takashi, Uchiyama Hirofumi, Yamamoto Noriko, Hori Hiroaki, Tatsumi Masahiko, Ishikawa Masanori, Arima Kunimasa, Higuchi Teruhiko, Kunugi Hiroshi
Abstract excerpt
Semaphorins are ligands of plexins, and the plexin-semaphorin signaling system is widely involved in many neuronal events including axon guidance, cell migration, axon pruning, and synaptic plasticity. The plexin A2 gene (PLXNA2) has been reported to be associated with schizophrenia. This finding prompted us to examine the possible association between the semaphorin 3D gene (SEMA3D) and schizophrenia in a...
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