Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A molecular mechanism for how sigma factor AlgT and transcriptional regulator AmrZ inhibit twitching motility in Pseudomonas aeruginosa

12 Mar 2020

Abstract excerpt

Pseudomonas aeruginosa isolates from cystic fibrosis patients are often mucoid (due to the overexpression of exopolysaccharide alginate) yet lost motility. It remains unclear about how P. aeruginosa coordinately regulates alginate production and the type IV pili-driven twitching motility. Here we showed that sigma 22 factor (AlgT/U), an activator of alginate biosynthesis, repressed twitching motility by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial biofilms and quorum sensing
Share to Bacterial Genetics and Biotechnology
Share to Cystic Fibrosis Research Advances

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32162778
DOI: 10.1111/1462-2920.14985

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A molecular mechanism for how sigma factor AlgT and transcriptional regulator AmrZ inhibit twitching motility in Pseudomonas aeruginosaPMID 32162778Read ↗

AmrZ modulates Pseudomonas aeruginosa biofilm architecture by directly repressing transcription of the psl operon.Semantic proximity Read ↗

Truncation of type IV pilin induces mucoidy in Pseudomonas aeruginosa strain PAO579.Semantic proximity Read ↗

The sigma factor AlgU plays a key role in formation of robust biofilms by nonmucoid Pseudomonas aeruginosa.Semantic proximity Read ↗

Cell wall stress activates expression of a novel stress response facilitator (SrfA) under σ22 (AlgT/U) control in Pseudomonas aeruginosa.Semantic proximity Read ↗

Novel proteins that modulate type IV pilus retraction dynamics in Pseudomonas aeruginosa.Semantic proximity Read ↗

The Alternative Sigma Factor AlgT RepressesPseudomonas aeruginosaFlagellum Biosynthesis by Inhibiting Expression offleQSemantic proximity Read ↗

Pseudomonas aeruginosa AmrZ Binds to Four Sites in the algD Promoter, Inducing DNA-AmrZ Complex Formation and Transcriptional Activation.Semantic proximity Read ↗

Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT, encoding a putative alternate sigma factor, and shows evidence for autoregulation.Semantic proximity Read ↗

Negative control of flagellum synthesis in Pseudomonas aeruginosa is modulated by the alternative sigma factor AlgT (AlgU).Semantic proximity Read ↗

Sigma factor-anti-sigma factor interaction in alginate synthesis: inhibition of AlgT by MucA.Semantic proximity Read ↗

Outer-membrane protein LptD (PA0595) plays a role in the regulation of alginate synthesis in Pseudomonas aeruginosa.Semantic proximity Read ↗

Overproduction of the AlgT sigma factor is lethal to mucoid <i>Pseudomonas aeruginosa</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.