Article
TRIM28 and TRIM27 are required for expressions of PDGFRβ and contractile phenotypic genes by vascular smooth muscle cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2020
Wang Yinfang, Hao Yilong, Zhao Yuanyuan, Huang Yitong, Lai Dongwu, Du Tao, Wan Xiaohong, Zhu Yuefeng, Liu Zongjun, Wang Ying, Wang Nanping, Zhang Peng
Abstract excerpt
Vascular smooth muscle cells (VSMCs) in the normal arterial media continually express contractile phenotypic markers which are reduced dramatically in response to injury. Tripartite motif-containing proteins are a family of scaffold proteins shown to regulate gene silencing, cell growth, and differentiation. We here investigated the biological role of tripartite motif-containing 28 (TRIM28) and tripartite...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
