Article

DJ-1 deficiency in SH-SY5Y cells reveals dysregulated networks of genes and pathways involved in neuronal function and disease

2024-11-01

Abstract excerpt

Parkinson’s disease (PD) is the second most common neurodegenerative disease, affecting between 2 – 3% of the population aged 65 and older. Although the etiology of idiopathic PD is still to be elucidated, the study of heritable forms of the disease can provide new understanding into disease mechanisms. Recessively inherited loss of function mutations in the PARK7/DJ-1 gene has been found to be causative for fami...

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Literature Corpus work: bac9781e-96a8-531f-8a88-1bb78a8c8535
DOI: 10.1101/2024.11.01.621572

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