Article
Culture of Small Colony Variant of Pseudomonas aeruginosa and Quantitation of its Alginate.
Journal of visualized experiments : JoVE - 22 Feb 2020
Al Ahmar Roy, Kirby Brandon D, Yu Hongwei D
Abstract excerpt
Pseudomonas aeruginosa, an opportunistic Gram-negative bacterial pathogen, can overproduce an exopolysaccharide alginate resulting in a unique phenotype called mucoidy. Alginate is linked to chronic lung infections resulting in poor prognosis in patients with cystic fibrosis (CF). Understanding the pathways that regulate the production of alginate can aid in the development of novel therapeutic strategies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
