Understanding the control of <i>Pseudomonas aeruginosa</i> alginate synthesis and the prospects for management of chronic infections in cystic fibrosis

Abstract excerpt

Decades of research have been dedicated to the study of the opportunistic pathogen Pseudomonas aeruginosa, a Gram-negative, environmental bacterium that secretes the exopolysaccharide alginate during chronic lung infection of cystic fibrosis (CF) patients. Although P. aeruginosa utilizes a variety of factors to establish a successful infection in the lungs of CF patients, alginate has stood out as one of the...

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