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Article

Effects of tryptophan, serotonin, and kynurenine on ischemic heart diseases and its risk factors: a Mendelian Randomization study.

European journal of clinical nutrition - 1 Apr 2020

Li Mengyu, Kwok Man Ki, Fong Shirley Siu Ming, Schooling Catherine Mary

Abstract excerpt

BACKGROUND/OBJECTIVES: Tryptophan is an essential amino acid that must be obtained from dietary items, such as dairy products, eggs, nuts, legumes, and grains, which are rich in tryptophan. It has also been suggested as a dietary supplement to improve mental health. Observationally plasma tryptophan is inversely associated with ischemic heart disease (IHD), however, its main metabolites, serotonin, and kynurenine...

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PMID: 32132674
DOI: 10.1038/s41430-020-0588-5

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