Article
ABCB1 variants C3435T and T129C are not associated with colorectal cancer risk.
African health sciences - 1 Sept 2019
Al Qahtani Areej M, Al-Ghafari Ayat B, Al Doghaither Huda A, Alzahrani Anas H, Omar Ulfat M, Rahimulddin Sawsan A
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) is one of the most prevalent cancers in Saudi Arabia that is highly characterized with poor survival rate and advanced metastasis. Many studies contribute this poor outcome to the expression of ABC transporters on the surface of cancer cells. OBJECTIVES: In this study, two ABCB1 variants, C3435T and T129C, were examined to evaluate their contribution to CRC risk. METHODS: 125...
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