CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma

Abstract excerpt

Adamantinomatous craniopharyngiomas (ACPs) are tumours of the sellar region and although histologically benign, they frequently invade the hypothalamus, visual tracts and local vascular structures. This aggressive behaviour can result in profound chronic morbidity, poor quality of life and increased mortality in long-term follow-up [1]. ACPs are histologically complex tumours with variable cystic, calcified and...

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