Article
MiRNA-146a Polymorphism Was Not Associated with Malaria in Southern India.
The American journal of tropical medicine and hygiene - 1 May 2020
van Loon Welmoed, Gai Prabhanjan P, Kulkarni Suyamindra S, Rasalkar Rashmi, Siegert Konrad, Wedam Jakob, Boloor Archith, Baliga Shantaram, Kumar Arun, Jain Animesh, Mahabala Chakrapani, Shenoy Damodara, Devi Rajeshwari, Gai Pramod, Mockenhaupt Frank P
Abstract excerpt
Micro-RNAs (miRNAs) play a crucial role in immune regulation, and a common miRNA-146a polymorphism (rs2910164) increased the odds of falciparum malaria in pregnant African women. Here, we examined whether this association holds true in a different population, that is, 449 mainly male and adult malaria patients and 666 community controls in southwestern India. Plasmodium vivax malaria (67%) predominated over...
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