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mRNAsi Index: Machine Learning in Mining Lung Adenocarcinoma Stem Cell Biomarkers

27 Feb 2020

Abstract excerpt

Cancer stem cells (CSCs), characterized by self-renewal and unlimited proliferation, lead to therapeutic resistance in lung cancer. In this study, we aimed to investigate the expressions of stem cell-related genes in lung adenocarcinoma (LUAD). The stemness index based on mRNA expression (mRNAsi) was utilized to analyze LUAD cases in the Cancer Genome Atlas (TCGA). First, mRNAsi was analyzed with differential...

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PMID: 32121037
DOI: 10.3390/genes11030257

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