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Integrative stemness characteristics associated with prognosis and the immune microenvironment in lung adenocarcinoma

5 Dec 2022

Abstract excerpt

BACKGROUND: To comprehensively analyze the stemness characteristics related to prognosis and the immune microenvironment in lung adenocarcinoma (LUAD). METHODS: The OCLR machine learning method was used to calculate the stemness index (mRNAsi) of the LUAD samples. DEGs common between the low mRNAsi, normal, and high mRNAsi groups were screened and the immune-stemness genes were obtained. Then the PPI network was...

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PMID: 36471379
DOI: 10.1186/s12890-022-02184-8

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