Article

A cancer stemness-related eight-gene signature for predicting prognosis and malignant degree of lung adenocarcinoma

2022-03-21

Abstract excerpt

To identify a cancer stemness-related prognostic signature, we analyzed RNA-seq data of patients with lung adenocarcinoma from the TCGA and GEO cohort using univariate Cox and LASSO analysis. Eight genes (PLEK2, GPX8, TCN1, PERP, CD79A, PAX5, FSCN1, and CNNM1) were eventually identified to develop a cancer stemness-related signature. AUCs for 5-year overall survival were 0.681, 0.673, and 0.774 in the training, va...

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Literature Corpus work: ff77496a-6d8a-55fb-8b70-7c4b867369d9
DOI: 10.21203/rs.3.rs-1442582/v1

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