Article

Integration of Single-cell and Bulk RNA Sequencing to Identify a Distinct Tumor Stem Cells and Construct a Novel Prognostic Signature for Evaluating Prognosis and Immunotherapy in LUAD

2024-08-17

Abstract excerpt

<title>Abstract</title> <p>Background Cancer stem cells (CSCs) play a crucial role in the progression of lung adenocarcinoma (LUAD).This study aimed to explore the gene signatures of tumor stem cells in LUAD through Single-cell RNA sequencing (scRNA-seq) data and bulk RNA sequencing (RNA-seq) data, and establish a tumor stem cell marker signature(TSCMS)prognostic risk model. Methods The LUAD scRNA-seq data and...

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Literature Corpus work: 3560aaa1-2709-5b6a-aed5-28a31cb7c4f9
DOI: 10.21203/rs.3.rs-4752786/v1

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