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A genetic variant in the promoter region of miR-877 is associated with an increased risk of hepatocellular carcinoma.

Clinics and research in hepatology and gastroenterology - 1 Oct 2020

Wang Hongtu, Wang Bo, Wang Tao, Fan Ruixuan

Abstract excerpt

INTRODUCTION: Genome wide association study has identified chromosome 6p21.33 as a risk locus of hepatocellular carcinoma (HCC). MiR-877 is located on this region, functioning as a tumor suppressor. The aim of this study was to investigate the association between rs1264440 in the promoter of miR-877 and HCC risk. MATERIALS AND METHODS: A total of 352 HCC patients and 359 age, gender, ethnicity and living area...

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PMID: 32113822
DOI: 10.1016/j.clinre.2020.01.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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