Article
Association between a variant in microRNA-646 and the susceptibility to hepatocellular carcinoma in a large-scale population.
TheScientificWorldJournal - 1 Jan 2014
Wang Rui, Zhang Jun, Jiang Weiru, Ma Yanyun, Li Wenshuai, Jin Bohan, Hu Heping, Wang Jiucun, Liu Yi, Liu Jie
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms in microRNAs play important roles in oncogenesis and cancer development. Objective. We aim to explore whether miR-646 rs6513497 is associated with the risk of hepatocellular carcinoma. METHODS: Total 997 HCC patients and 993 cancer-free controls were enrolled in this study. Genotyping was performed using MassARRAY method. RESULTS: Compared with the T allele of...
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