Article
Identification of miR-423 and miR-499 polymorphisms on affecting the risk of hepatocellular carcinoma in a large-scale population.
Genetic testing and molecular biomarkers - 1 Jul 2014
Ma Yanyun, Wang Rui, Zhang Jun, Li Wenshuai, Gao Chunfang, Liu Jie, Wang Jiucun
Abstract excerpt
AIMS: MicroRNAs (miRNAs) regulate gene expression and act as tumor suppressors or enhancers in oncogenesis. Single-nucleotide polymorphisms (SNPs) in miRNAs could alter the processing or actions of mature miRNA. So far, the association of miR-423 rs6505162 with cancers has not been explored, while the association of miR-499 rs3746444 was only reported in small-sized samples of different types of populations....
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