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Article

Development of Oxytolerant Salmonella typhimurium Using Radiation Mutation Technology (RMT) for Cancer Therapy.

Scientific reports - 28 Feb 2020

Gao Shuang, Jung Jong-Hyun, Lin Shun-Mei, Jang A-Yeung, Zhi Yong, Bum Ahn Ki, Ji Hyun-Jung, Hyang Lim Jae, Guo Huichen, Choy Hyon E, Lim Sangyong, Seo Ho Seong

Abstract excerpt

A critical limitation of Salmonella typhimurium (S. typhimurium) as an anti-cancer agent is the loss of their invasive or replicative activities, which results in no or less delivery of anti-cancer agents inside cancer cells in cancer therapy. Here we developed an oxytolerant attenuated Salmonella strain (KST0650) from the parental KST0649 (ΔptsIΔcrr) strain using radiation mutation technology (RMT). The...

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Identifiers

PMID: 32111878
DOI: 10.1038/s41598-020-60396-6
PMCID: PMC7048768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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