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Article

CORP: Using transgenic mice to study skeletal muscle physiology.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 May 2020

Mobley C Brooks, Vechetti Ivan J, Valentino Taylor R, McCarthy John J

Abstract excerpt

The development of tissue-specific inducible transgenic mice has provided a powerful tool to study gene function and cell biology in almost any tissue of interest at any given time within the animal's life. The purpose of this review is to describe how to use two different inducible transgenic systems, the Cre-loxP system and the Tet-ON/OFF system, that can be used to study skeletal muscle physiology. Myofiber-...

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Identifiers

PMID: 32105520
DOI: 10.1152/japplphysiol.00021.2020
PMCID: PMC7272760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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