Article
Four SNPs and Systemic Level of FOXP3 in Smokers and Patients with Chronic Obstructive Pulmonary Disease.
COPD - 1 Dec 2016
Chu Shuyuan, Zhong Xiaoning, Zhang Jianquan, Lai Xiaoying, Xie Jiajun, Li Yu
Abstract excerpt
Forkhead box P3 (FOXP3) is the essential transcription factor for the function of regulatory T-cell (Treg). However, the gene mutation of FOXP3 in patients with chronic obstructive pulmonary disease (COPD) at different stages has not been reported. We aim to investigate four single nucleotide polymorphisms (SNPs) and the mRNA expression of FOXP3 in smokers with normal lung function and smokers with COPD at...
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