Article
Impact of FOXP3 gene polymorphisms and gene-environment interactions in asthma and atopy in a Brazilian population.
Gene - 5 Sept 2022
Marques Cintia Rodrigues, Fiuza Bianca Sampaio Dotto, da Silva Thiago Magalhães, Carneiro Tamires Cana Brasil, Costa Ryan Santos, de Assis Silva Monica Francisca, Viana Wagma Lauane Luz, Carneiro Valdirene Leão, Alcantara-Neves Neuza Maria, Barreto Maurício Lima, Figueiredo Camila Alexandrina
Abstract excerpt
BACKGROUND: Polymorphisms in genes related to the activation and development of regulatory T cells (Tregs), such as FOXP3, may be associated with asthma and atopy development. Additionally, environmental factors such as exposure to infections can modify the effect of these associations. This study evaluated the impact of polymorphisms in the FOXP3 on the risk of asthma and atopy as also gene-environment...
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