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Cancer stem cell contribution to glioblastoma invasiveness

28 Feb 2013

Abstract excerpt

Glioblastoma (GBM) is the most aggressive and lethal brain tumor in adults. Its invasive nature currently represents the most challenging hurdle to surgical resection. The mechanism adopted by GBM cells to carry out their invasive strategy is an intricate program that recalls what takes place in embryonic cells during development and in carcinoma cells during metastasis formation, the so-called...

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PMID: 23510696
DOI: 10.1186/scrt166

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