Article
The role of kynurenine pathway and kynurenic aminotransferase alleles in postpartum depression following cesarean section in Chinese women.
Brain and behavior - 1 Apr 2020
Quan Chengxuan, Wang Saiying, Duan Kaiming, Ma Jiahui, Yu Heya, Yang Mi, Hu Na, Long Ge, Zeng Guang, Huang Zhendong
Abstract excerpt
OBJECTIVES: A growing body of data indicates that the kynurenine pathway may play a role in the pathogenesis of postpartum depressive symptoms (PDS). Kynurenic aminotransferase (KAT) is an important kynurenine pathway enzyme, catalyzing kynurenine (KYN) into kynurenic acid (KYNA). This study investigated as to whether genetic variations in KAT are associated with PDS. METHODS: A cohort of 360 Chinese women...
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