Article
Association of QPRT gene polymorphisms with postpartum depression in Chinese cesarean parturients: A candidate gene association study.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 28 Dec 2025
Zhao Shanshan, Lin Guoxin, Li Ziyuan, Ping Anqi, Wang Saiying, Duan Kaiming
Abstract excerpt
OBJECTIVES: Postpartum depression (PPD) is a common and serious mental disorder after childbirth, imposing a heavy burden on mothers, infants, and families. Abnormalities in the tryptophan-kynurenine (TRP-KYN) metabolic pathway are considered to be involved in its pathogenesis, but the role of quinolinic acid phosphoribosyltransferase (QPRT), a key downstream enzyme in this pathway, remains unclear. This study...
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