Article
The IDO genetic polymorphisms and postpartum depressive symptoms: an association study in Chinese parturients who underwent cesarean section.
Archives of women's mental health - 1 Jun 2019
Duan Kai-Ming, Wang Sai-Ying, Yin Ji-Ye, Li Xi, Ma Jia-Hui, Huang Zhen-Dong, Zhou Ying-Yong, Yu He-Ya, Yang Mi, Zhou Hong-Hao, Liu Zhao-Qian
Abstract excerpt
Postpartum depressive symptoms (PDS) are not an uncommon mood disorder in postpartum women. Our previous research indicated a role for increased tryptophan (TRP) metabolism along the kynurenine pathway (KP) in the pathogenesis of PDS. Accordingly, this study was going to investigate the association of indoleamine-2,3-dioxygenase (IDO, a key enzyme of KP) genetic polymorphisms with PDS. Seven hundred twenty-five...
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