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Article

Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women.

Journal of affective disorders - 1 Jun 2017

Wang Sai-Ying, Duan Kai-Ming, Tan Xiao-Fang, Yin Ji-Ye, Mao Xiao-Yuan, Zheng Wei, Wang Chun-Yan, Yang Mi, Peng Cheng, Zhou Hong-Hao, Liu Zhao-Qian

Abstract excerpt

BACKGROUND: New conceptualizations of depression have emphasized the role of the kynurenine pathway (KP) in the pathogenesis of postpartum depressive symptoms (PDS). Kynurenine 3-monooxygenase (KMO) is a rate-limiting enzyme of the KP, where it catalyzes the conversion of kynurenine (KYN) to 3-hydroxykynurenine (3-HK). Previous work indicates that KMO is closely linked to the pathophysiology of depressive...

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Identifiers

PMID: 28319697
DOI: 10.1016/j.jad.2017.03.023

Genes

KMO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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