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Article

Juvenile papillomatosis of the breast (Swiss cheese disease) has frequent associations with PIK3CA and/or AKT1 mutations.

Human pathology - 1 Apr 2020

Guillet Carole, Rechsteiner Markus, Bellini Elisa, Choschzick Matthias, Moskovszky Linda, Dedes Konstantin, Papassotiropoulos Bärbel, Varga Zsuzsanna

Abstract excerpt

Juvenile papillomatosis (JP), the so-called Swiss cheese disease, is a rare benign breast disease of young adults. An association (up to 28%) with breast cancer within the family of affected patients has been reported. A multinodular cystic breast mass lesion and calcifications characterizes JP in imaging studies. The histological picture is diverse and comprises multiple intraductal papillomas, usual ductal...

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Identifiers

PMID: 32088208
DOI: 10.1016/j.humpath.2020.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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