Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recurrent bilateral giant breast fibroadenomas with a somatic PIK3CA p.G106V mutation: case report and review of current evidence.

BMC women's health - 21 Oct 2025

Zhang Yuemei, Tan Qixing, Xiao Yugui, Wang Wenhao, Huang Shengkai, Mo Qinguo, Zhang Wenhai, Wei Wei

Abstract excerpt

BACKGROUND: Fibroadenomas are common benign breast tumors, but recurrent bilateral giant fibroadenomas are rare. Recent studies suggest genetic factors, such as PIK3CA mutations, may influence tumor behavior. CASE PRESENTATION: A 23-year-old woman with prior multiple fibroadenoma excisions presented with progressively enlarging bilateral breast masses and marked deformity. Imaging revealed multiple...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Class I Phosphatidylinositol 3-Kinases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to PIK3CA gene

Share to Mutation

Share to Neoplasm Recurrence, Local

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 41121210
DOI: 10.1186/s12905-025-04032-3
PMCID: PMC12539028

Genes

PIK3CA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recurrent bilateral giant breast fibroadenomas with a somatic PIK3CA p.G106V mutation: case report and review of current evidence.PMID 41121210Read ↗

A Case Report of Recurrent Bilateral Giant Fibroadenomas in a Young Woman with PIK3CA MutationSemantic proximity Read ↗

Early Onset, Multiple, Bilateral Fibroadenomas of the Breast: A Case ReportSemantic proximity Read ↗

Genetics and genomics of breast fibroadenomas.Semantic proximity Read ↗

Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.Semantic proximity Read ↗

Giant cell tumor of soft tissue of the breast: Case report with H3F3A mutation analysis and review of the literature.Semantic proximity Read ↗

BIA-ALCL and BIA-SCC: Updates on Clinical Features and Genetic Mutations for Latest Recommendations.Semantic proximity Read ↗

Tumor phenotype and concordance in synchronous bilateral breast cancer in young women.Semantic proximity Read ↗

A clinical report and analysis of metachronous multiple primary cancers occurred in four sitesSemantic proximity Read ↗

Assessment of HMGA2 and PLAG1 rearrangements in breast adenomyoepitheliomasSemantic proximity Read ↗

Genetics of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL).Semantic proximity Read ↗

Infiltrating epitheliosis of the breast: characterization of histological features, immunophenotype and genomic profile.Semantic proximity Read ↗

Adenomyoepitheliomas of the Breast Frequently Harbor Recurrent Hotspot Mutations in PIK3-AKT Pathway-related Genes and a Subset Show Genetic Similarity to Salivary Gland Epithelial-Myoepithelial CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.