Article
Impacts of interactions between ADH1B and ALDH2 genotypes on alcohol flushing, alcohol reeking on the day after drinking, and age distribution in Japanese alcohol-dependent men.
Pharmacogenetics and genomics - 1 Apr 2020
Yokoyama Akira, Yokoyama Tetsuji, Matsui Toshifumi, Mizukami Takeshi, Kimura Mitsuru, Matsushita Sachio, Higuchi Susumu, Maruyama Katsuya
Abstract excerpt
OBJECTIVE: This study sought to evaluate the impacts of interactions between the alcohol dehydrogenase-1B (rs1229984) genotype and the aldehyde dehydrogenase-2 (rs671) genotype on alcohol flushing, alcohol reeking on the day after drinking, and the age distribution in alcohol-dependent patients. METHODS: The study subjects were 4107 Japanese alcohol-dependent men who underwent alcohol dehydrogenase-1B and...
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