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Article

The Importance of Cancer-Associated Fibroblasts in the Pathogenesis of Head and Neck Cancers.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti - 1 Jan 2020

Raudenská Martina, Svobodová Markéta, Gumulec Jaromír, Falk Martin, Masařík Michal

Abstract excerpt

BACKGROUND: Despite progress in anticancer therapies, head and neck squamous cell carcinoma (HNSCC) has still a low survival rate. Recent studies have shown that tumour stroma may play an important role in the pathogenesis of this malignant disease. Fibroblasts are a major component of the tumour microenvironment and may significantly influence HNSCC progression as indicated by the contribution they make to...

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PMID: 32075388
DOI: 10.14735/amko202039

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