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Article

Tumor microenvironment in head and neck squamous cell carcinoma.

Seminars in oncology - 1 Apr 2014

Curry Joseph M, Sprandio John, Cognetti David, Luginbuhl Adam, Bar-ad Voichita, Pribitkin Edmund, Tuluc Madalina

Abstract excerpt

The tumor microenvironment (TME) of head and neck squamous cell carcinoma (HNSCC) is comprised of cancer-associated fibroblasts (CAFs), immune cells, and other supporting cells. Genetic changes in the carcinoma cells, such as alterations to TP53, NOTCH1, and specific gene expression profiles, con...

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Source

Identifiers

PMID: 24787294
DOI: 10.1053/j.seminoncol.2014.03.003

Genes

NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24787294-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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