Article
Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia.
Journal of the National Cancer Institute - 1 Apr 2014
Park S Lani, Fesinmeyer Megan D, Timofeeva Maria, Caberto Christian P, Kocarnik Jonathan M, Han Younghun, Love Shelly-Ann, Young Alicia, Dumitrescu Logan, Lin Yi, Goodloe Robert, Wilkens Lynne R, Hindorff Lucia, Fowke Jay H, Carty Cara, Buyske Steven, Schumacher Frederick R, Butler Anne, Dilks Holli, Deelman Ewa, Cote Michele L, Chen Wei, Pande Mala, Christiani David C, Field John K, Bickebller Heike, Risch Angela, Heinrich Joachim, Brennan Paul, Wang Yufei, Eisen Timothy, Houlston Richard S, Thun Michael, Albanes Demetrius, Caporaso Neil, Peters Ulrike, North Kari E, Heiss Gerardo, Crawford Dana C, Bush William S, Haiman Christopher A, Landi Maria Teresa, Hung Rayjean J, Kooperberg Charles, Amos Christopher I, Le Marchand Loïc, Cheng Iona
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified hundreds of genetic variants associated with specific cancers. A few of these risk regions have been associated with more than one cancer site; however, a systematic evaluation of the associations between risk variants for other cancers and lung cancer risk has yet to be performed. METHODS: We included 18023 patients with lung cancer and 60543 control...
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