Article
Association between GSTP1, GSTM1 and GSTT1 polymorphisms involved in xenobiotic metabolism and head and neck cancer development.
Molecular biology reports - 1 Jul 2013
Russo Anelise, Francelin Pamela Risardi, Galbiatti Ana Lívia Silva, Raposo Luis Sérgio, Maníglia José Victor, Pavarino Erika Cristina, Goloni-Bertollo Eny Maria
Abstract excerpt
Polymorphisms in the glutathione S-transferase superfamily genes that encodes enzymes involved in the phase II xenobiotic metabolism may lead head and neck cancer development. In this study we investigate the association of A313G and C341T GSTP1 polymorphisms, GSTM1 and GSTT1 null genotypes in the head and neck cancer development, interactions between these polymorphisms,the tumor histopathologic parameters and...
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