Article
Association of genetic polymorphisms in glutathione S-transferases and susceptibility to head and neck cancer.
Mutation research - 1 Feb 2008
Singh Madhu, Shah Parag P, Singh Arvind P, Ruwali Munindra, Mathur Neeraj, Pant Mohan C, Parmar Devendra
Abstract excerpt
Polymorphism in glutathione S-transferase (GST) genes (GSTM1, GSTT1 and GSTP1) and interaction with environmental factors such as tobacco (smoking or chewing) and alcohol on susceptibility to head and neck squamous cell carcinoma (HNSCC) was studied in a case-control study. The study group consisted of 175 patients suffering from HNSCC and 200 age matched healthy controls. Statistical analysis showed an increase...
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