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Article

Toll-like receptor 4 polymorphisms in dengue virus-infected children.

The American journal of tropical medicine and hygiene - 1 Aug 2011

Djamiatun Kis, Ferwerda Bart, Netea Mihai G, van der Ven André J A M, Dolmans Wil M V, Faradz Sultana M H

Abstract excerpt

Differential viral recognition by cells bearing Toll-like receptor 4 (TLR4) polymorphisms Asp299Gly and Thr399Ile may influence susceptibility and severity of dengue virus infection. In central Java, Indonesia, we investigated 201 children with dengue hemorrhagic fever (DHF) and 179 healthy controls. Patients and controls were mostly ethnic Javanese. A nearly complete cosegregation of the two mutations was...

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Identifiers

PMID: 21813858
DOI: 10.4269/ajtmh.2011.10-0728
PMCID: PMC3144836

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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